diff --git a/cocos/editor-support/cocostudio/ActionTimeline/CCFrame.cpp b/cocos/editor-support/cocostudio/ActionTimeline/CCFrame.cpp
index fd74cc0237..daf6cd18f2 100644
--- a/cocos/editor-support/cocostudio/ActionTimeline/CCFrame.cpp
+++ b/cocos/editor-support/cocostudio/ActionTimeline/CCFrame.cpp
@@ -225,7 +225,7 @@ void RotationFrame::onEnter(Frame *nextFrame, int currentFrameIndex)
 
 void RotationFrame::onApply(float percent)
 {
-    if (_betwennRotation != 0)
+    if (nullptr != _node && _betwennRotation != 0)
     {
         float rotation = _rotation + percent * _betwennRotation;
         _node->setRotation(rotation);
@@ -282,7 +282,7 @@ void SkewFrame::onEnter(Frame *nextFrame, int currentFrameIndex)
 
 void SkewFrame::onApply(float percent)
 {
-    if (_betweenSkewX != 0 || _betweenSkewY != 0)
+    if (nullptr != _node && _betweenSkewX != 0 || _betweenSkewY != 0)
     {
         float skewx = _skewX + percent * _betweenSkewX;
         float skewy = _skewY + percent * _betweenSkewY;
@@ -342,7 +342,7 @@ void RotationSkewFrame::onEnter(Frame *nextFrame, int currentFrameIndex)
 
 void RotationSkewFrame::onApply(float percent)
 {
-    if (_betweenSkewX != 0 || _betweenSkewY != 0)
+    if (nullptr != _node && _betweenSkewX != 0 || _betweenSkewY != 0)
     {
         float skewx = _skewX + percent * _betweenSkewX;
         float skewy = _skewY + percent * _betweenSkewY;
@@ -400,7 +400,7 @@ void PositionFrame::onEnter(Frame *nextFrame, int currentFrameIndex)
 
 void PositionFrame::onApply(float percent)
 {
-    if (_betweenX != 0 || _betweenY != 0)
+    if (nullptr != _node && _betweenX != 0 || _betweenY != 0)
     {
         Point p;
         p.x = _position.x + _betweenX * percent;
@@ -460,7 +460,7 @@ void ScaleFrame::onEnter(Frame *nextFrame, int currentFrameIndex)
 
 void ScaleFrame::onApply(float percent)
 {
-    if (_betweenScaleX != 0 || _betweenScaleY != 0)
+    if (nullptr != _node && _betweenScaleX != 0 || _betweenScaleY != 0)
     {
         float scaleX = _scaleX + _betweenScaleX * percent;
         float scaleY = _scaleY + _betweenScaleY * percent;
@@ -694,7 +694,7 @@ void ColorFrame::onEnter(Frame *nextFrame, int currentFrameIndex)
 
 void ColorFrame::onApply(float percent)
 {
-    if (_betweenRed != 0 || _betweenGreen != 0 || _betweenBlue != 0)
+    if (nullptr != _node && _betweenRed != 0 || _betweenGreen != 0 || _betweenBlue != 0)
     {
         Color3B color;
         color.r = _color.r+ _betweenRed   * percent;
@@ -750,8 +750,11 @@ void AlphaFrame::onEnter(Frame *nextFrame, int currentFrameIndex)
 
 void AlphaFrame::onApply(float percent)
 {
-    GLubyte alpha = _alpha + _betweenAlpha * percent;
-    _node->setOpacity(alpha);
+    if (nullptr != _node)
+    {
+        GLubyte alpha = _alpha + _betweenAlpha * percent;
+        _node->setOpacity(alpha);
+    }
 }
 
 Frame* AlphaFrame::clone()